It depends on the size of the snake. I've never been bitten by Princess but my baby boa tagged me about a month ago. I just thought that she'd butted me until I saw the blood, it was less painful than being flicked. It did sting a little afterwards, but nothing to worry about.
So long as the snake ain't full grown adult you normally won't notice. Most bites are warning shots and they don't tend to hold on. Even in the wild Royals are known to be non biters.